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MOTOR
NEURON DISEASES
What is ALS?
Amyotrophic lateral sclerosis, ALS, is a motor neuron disease characterized
by degeneration of motor neurons in the brain, brainstem and spinal cord.
This leads to progressive paralysis of the limbs, the diaphragm and the
muscles of chewing, speaking and swallowing. Because ALS only affects
motor neurons, it generally does not impair intelligence, memory, or sensory
function.
There is no primary treatment for this diseases although many symptomatic
therapies are helpful.
There are two types of ALS: sporadic and familial. Sporadic ALS accounts
for 90% of the cases. Familial ALS (FALS) accounts for the remaining 10%
of cases. Familial ALS is identified when more than one member of the
same family develops the disease.
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